We studied the inter-species relationships and biogeography of the genus Odorrana. 29 morphological characters of 16 species of Odorrana were studied with PAUP3.1,their geographic distribution were analyzed by migration thesis. The cladogram shown that the Odorrana species were of monophyleticly origin and could be divided into four groups. ① andersonii group:Odorrana margaretae,O. andersonii,O. grahami,O. hainangensis:② kuangwuensis group:O. kuangwuensis,O. wuchuanensis. ③ schmackeri group:O. hejiangensis,O. tiannanensis,O. anlungensis,O. schmackeri,O. lungshengensis,O. swinhoana. ④ livida group: O. livida,O. exiliversabilis,O. versabilis,O. nasuta. The inter-species relationships show that andersonii group had the most amount plesiomorphy,so they were suggested as the most primitive species in the genus Odorrana. Because the most primitive species are distributed in Mt. Hengduan and Plateau of western Yunnan, thus Mt. Hengduan and Plateau of western Yunnan are probably the original regions of Odorrana. Eight species,accounting for 50% of the total number of Odorrana species in China,were discovered in Guizhou Plateau,and all four species groups had representative species in the area. Therefore,this area was the transition zone of odor frogs migrated from western China to southeastern China. Accordingly,the Guizhou Plateau is probably the center of diversification of Odorrana. The livida group with more apomorphic characters is distributed in eastern, southern parts and islands of China,the group is evolutionary species group in the genus. Along the distributed regions,the substitution of species within a species-group was found from south to north (see Fig.2),the substitution among species-groups was found from west to east,andersonii group-kuangwuensis group-schmackeri group-livida group. The primitive species distribute in southwestern part of China,and the evolutionary species in eastern,southeastern parts and islands of China. The livida group is more closely related to schmackeri group than to kuangwuensis group,and is more distantly to andersonii group. These relationships among species groups are coincided very well with their distributional pattern.